I use Visual Studio 2008 Professional in the office, and have recently discovered Scott Hanselman’s blog post on Visual Studio themes.
I’m finding Brad Wilsons Dark Visual Studio theme very easy on my eyes.
If you’re still using the default visual studio theme, check out Scott’s post for some other alternatives, I’m finding it a lot easier on my eyes staring at a black screen all day (and night…) instead of a white one.